
Highlights
Age Groups Seen
- Adults
Languages
- English
Gender
FemaleAbout Mary S O'Brien
Biography/ Philosophy of Care
Mary S. O’Brien, M.D., is an obstetrician and gynecologist with Total Woman, a Part of Norton Women’s Care. Dr. O’Brien earned her medical degree from the University of Louisville School of Medicine. She completed her residency in obstetrics and gynecology at University of Louisville Hospital.
Her clinical interests include caring for women throughout the phases of their lives, from adolescence through their reproductive years and into menopause. She has a special interest in minimally invasive surgery techniques, including laparoscopic and robotic surgery. Her goal is to ensure that every patient feels heard regarding their health care concerns and supported in their personal decisions. She aims to provide individualized care and work alongside her patients to determine the best care plan for them.
Outside of work, Dr. O’Brien enjoys spending time with her family. She loves attending University of Louisville sporting events, spending time outside and trying new restaurants.
Video
Locations
- Total Woman, a Part of Norton Women's Care
- 4123 Dutchmans Lane, Suite 500, Louisville, KY 40207
- Get Directions
- phone: 502-894-9494
- fax: 502-894-9404
Expertise
Education
- Residency: University of Louisville School of Medicine, Obstetrics & Gynecology, 2024
- Medical Education: University of Louisville, Doctor of Medicine, 2020
Insurance
- Aetna
- Aetna Better Health
- Aetna Medicare Advantage
- Ambetter from MHS
- Ambetter from WellCare of Kentucky
- Anthem
- Anthem Indiana Medicaid
- Anthem MediBlue HMO/PPO
- Anthem Pathway
- Anthem Pathway Transition
- CareSource Indiana Medicaid
- CareSource Marketplace Kentucky and Indiana
- Cigna
- CorVel
- Coventry
- Encore
- Essence
- First Health Group Corp. (First Health)
- HealthSmart
- Hosparus
- Humana Medicaid
- Humana Medicare
- Indiana Health Network
- Indiana Medicaid
- Indiana Medicare
- Kentucky Medicaid
- Kentucky Medicare
- MDwise
- MHS
- Molina Healthcare
- MultiPlan
- Passport Health Plan Kentucky MCO
- Passport Marketplace
- Provider Net/OMCA
- Sagamore
- Signature Advantage
- SIHO
- TRICARE Humana Military
- United Healthcare
- United Healthcare Community Plan Indiana and Kentucky
- United Healthcare Medicare Advantage
- UofL Health – Frazier Rehabilitation Institute
- Veterans Affairs (VA)
- WellCare
- WellCare Medicare
- WellCare of Kentucky Medicaid (Kentucky MCO)
- Wellpath
- Workers’ Compensation
Ratings & Reviews
4.9 out of 5
64 ratings, 25 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 2/7/2026
Dr. O Brian was great. Talked about any concerns I had and explained things in detail.Very positive and felt very comfortable around her
- 5 out of 5 starsReviewed on 1/24/2026
Dr O'Brien is a wonderful provider. I cannot say enough good things about her. She always listens to my concerns and answers my questions without ever making me feel rushed or unimportant or silly. She is top notch!
- 5 out of 5 starsReviewed on 1/21/2026
Dr. O'Brien walked in the room and immediately asked to see pictures of my kids. She did not make me feel rushed at ALL. She is who I will continue to see!!
- 5 out of 5 starsReviewed on 1/18/2026
She knew what she was talking about.
- 5 out of 5 starsReviewed on 1/15/2026
Dr. O'Brien was the best provider I could've asked for. I had not seen an OBGYN in a few years because it was difficult for me to find a doctor like her. She met all the desires I had!
- 5 out of 5 starsReviewed on 12/11/2025
Got in early. Very efficient.
- 5 out of 5 starsReviewed on 11/23/2025
Very courteous and knowledgeable. Answered all my questions and concerns.
- 4 out of 5 starsReviewed on 11/22/2025
Explained things thoroughly. Allowed time for me to ask questions.Not pushy
- 5 out of 5 starsReviewed on 11/20/2025
Dr. O'Brian provided compassionate and informed care during my visit. No changes needed about our discussion and plans for surgery.
- 5 out of 5 starsReviewed on 11/3/2025
This provider was outstanding. Answered all my questions and concerns. Wish every provider was like this!!!
- 5 out of 5 starsReviewed on 10/25/2025
Very nice, comfortable, professional, easy to talk to about concerns
- 5 out of 5 starsReviewed on 10/17/2025
Professional and nice. I have been with this practice along time. All Dr's I have had there were very good. This visit the staff noticed my birthday was coming up and said Happy Birthday.
- 5 out of 5 starsReviewed on 10/6/2025
Very polite, understanding, caring and considered about my health.
- 5 out of 5 starsReviewed on 10/6/2025
Everyone was so kind and thoughtful during our appointment. I was blown away at the kindness displayed.
- 5 out of 5 starsReviewed on 9/7/2025
Wonderful physician. Great interpersonal skills matching her clinical skills. Highly recommend.
- 5 out of 5 starsReviewed on 8/27/2025
Everyone I came in contact with were extremelyNice.
- 5 out of 5 starsReviewed on 8/15/2025
She's great and very knowledgeable. Very detail oriented and makes you feel confident. She's great
- 5 out of 5 starsReviewed on 8/12/2025
After my gynecologist, [...], retired last year, I was very concerned about having a doctor that would care about my gyn Issues. Dr. O'Brien was wonderful, caring, knowledgeable and I couldn't ask for a better Doctor.
- 5 out of 5 starsReviewed on 8/8/2025
Dr. O'Brien is very kind and explains exactly what to expect from each appointment. I have never felt rushed during appointments with Dr. O'Brien, she takes her time and listens to patient concerns. She does a great job at answering all questions.
- 5 out of 5 starsReviewed on 8/8/2025
Dr. O'Brien really listened to my concerns and helped me figure out a plan for my issue. I got to my appointment thirty minutes early and they still took me back, I was out by my appointment time. Her medical assistant was so sweet and was really concerned about my blood pressure and her concern for me just meant the world.
- 5 out of 5 starsReviewed on 7/31/2025
She is extremely nice and patient plus very professional
- 5 out of 5 starsReviewed on 7/28/2025
Dr. O'Brien was amazing with her care! I know that she will be a great addition to my care plan going forward.
- 5 out of 5 starsReviewed on 6/13/2025
She was very sweet and made me feel like she truly cares about each individual patient.
- 5 out of 5 starsReviewed on 6/8/2025
Dr. O'Brien was a new doctor to me as [...] has retired. Smooth transition from one doctor to another doctor.
- 5 out of 5 starsReviewed on 6/2/2025
This was my first visit with Dr. O'Brien, and honestly, I was pretty nervous about switching doctors after being with the same OB for years. But she immediately put me at ease, she took her time, listened to all my concerns, and walked me through every option with so much care and detail. I really appreciated how open she was and how willing she was to answer all my (possibly silly) questions. I left the appointment feeling really good about my care and confident moving forward.